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Affiliation Marketing for online pharma: the compliant playbook

Networks, attribution, AIFA compliance, traffic quality. Four years of mistakes summarized in an operating framework.

28 Mar 2026 · 11 min · Roberta D.

Online pharma + affiliation is one of the few sectors where a marketing mistake can become a regulatory problem. Four years working with pharmacy clients taught us how to build a playbook that works and doesn't upset AIFA (the Italian medicines agency).

Networks: fewer and selected is better. We closed more than twenty partnerships where traffic quality was lower than the commission cost. 'Open' networks generate noise, not revenue.

Attribution: data-driven model, 30-day window, post-view excluded. The reality is that many 'affiliation' conversions would have arrived anyway. Measuring well is more important than paying less.

AIFA compliance: every creative goes through internal legal review before going live. No therapeutic claims, no before/after, no unverified testimonials. The network must sign a specific addendum.

Traffic quality: we monitor bounce, time on cart, return rate. A publisher who brings 1,000 clicks with 80% bounce is worth less than one who brings 100 at 12%. We cut without nostalgia.

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